History

Scale-up Systems Ltd. is a privately held technology company founded in 1994, owned by executives, staff and institutional investors.

The early history of Scale-up Systems is as a process consultancy organisation and innovator in software development for chemical reactions and Computational Fluid Dynamics (CFD).

DynoChem was originally developed at Zeneca in the mid-1990s by Frans Muller under the leadership of Keith Carpenter. The project was initiated because no commercially-available software existed to meet the team's requirements of:

  • Multi-phase reaction modelling
  • A familiar user interface that any data could be brought into quickly
  • Minimizing the need to write equations so it could be used by any scientist or engineer

Following its successful application to a range of consulting and troubleshooting projects, Scale-up Systems acquired the full rights to commercialize, develop and support DynoChem in 2000.

Today Scale-up Systems is dedicated to producing the best software, training and support for the pharmaceutical and related industries to accelerate process development and to facilitate right first time scale-up and continuous improvement in API manufacturing.

An example of Scale-up Systems commitment to the pharmaceutical industry is sponsorship of the AIChE Award for Excellence in QbD (Quality by Design) for Drug Substance.

Scale-up Systems hosts a software development team at its Headquarters in Dublin, Ireland and has a global reach, with a growing team of support, training and sales personnel in North America, Europe and India.

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News

Dr Wilfried Hoffmann joins Scale-up Systems as a Principal Consultant with over 28 years experience in API development in the pharmaceutical industry. [Jan-2012]

Swiss-based pharmaceutical company increases deployment of DynoChem for use by scientists and engineers. [Dec-2011]

Irish pharmaceutical manufacturing site selects DynoChem for process optimization and QbD initiatives. [Nov-2011]

World-leading speciality chemicals company in Middle East selects DynoChem to support their scale-up and QbD initiatives. [Oct-2011]

Jose Tabora (BMS) wins DynoChem’s QbD award at 2011 AIChE Meeting in Minneapolis. [Oct-2011]

Biggest Indian Multi-national Pharma company selects DynoChem for technology transfer and scale-up activities. [Sep-2011]

New customer selects DynoChem to assist in safe manufacturing of energetic materials. [Sep-2011]

Scale-up Systems India launched to provide a local service to customers. [Aug-2011]

Two new Universities join Academic Program. [Aug-2011]

Two new API manufacturers select DynoChem to support their process development initiatives. [Jul-2011]

New CRO customer selects DynoChem for adding value to solid phase projects. [Jun-2011]

European User Meeting held in London. [May-2011]

North American User Meeting held in Chicago. [May-2011]

Indian User Meeting held in Mumbai. [Apr-2011]

New API manufacturer selects DynoChem for process improvement projects. [Apr-2011]

DynoChem 2011 is released. [Apr-2011]