Reaction kinetics and optimization of the copper-catalyzed oxidation of ApoA-1M
This paper summarizes the development of an optimized Cu(II)-catalyzed oxidation process for the dimer formation of ApoA-1M, the protein component of an HDL mimic with potential efficacy in atherosclerotic plaque reduction.
Unit Operation: Process
Objective: Kinetics, Optimization
Company: Pfizer
Source: Chemical Engineering Science, Volume 64, Issue 11, 1 June 2009, Pages 2623-2630
Authors: Robert L. Dufield (Pfizer), John T. Herberg (Pfizer), Sa V. Ho (Pfizer), Alan K. Hunter (Pfizer), Joseph McLaughlin (Pfizer), Eric Suda (Pfizer), Kristen E. Thomas (Pfizer)
Publish Date: 05-Mar-2009
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