O-Phenylisourea Synthesis and Deprotonation: Carbodiimide Elimination Precludes the Reported Chapman Rearrangement
The kinetics of the addition of phenol to diisopropylcarbodiimide, and reaction of the resulting N,N′-diisopropyl-O-phenylisourea with hydroxide, are reported.
Unit Operation: Reaction
Objective: Kinetics
Company: Syngenta, University of Edinburgh
Source: European Journal of Organic Chemistry, Volume 2016, Issue 16, June 2016, Pages 2821–2827
Authors: George Hodges (Syngenta), Guy C. Lloyd-Jones (University of Edinburgh), Joseph A. Tate (University of Edinburgh)
Publish Date: 23-May-2016
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