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Robust Tech Transfer Packages

Robust packages for up-scaling and tech transfer help ensure that pilot trials are completed in the window available, scale-up to manufacturing works right-first-time and that outsourcing production is successful.

DynoChem models become part of the tech transfer package and scale-up discussion. Users are confident of scale-up and tech transfer success as they are able to make the correct equipment choices and identify suitable operating conditions.

  • DynoChem models contain data and scale-up information to achieve Key Performance Indicators
  • DynoChem Heat Transfer and Mixing Utilities are developed for performance comparison between vessels

What our users say:
"The tool is used for a wide range of vessel sizes (40 to 10,000 L). The thermal scale-up simulation is used prior to production to identify the "right" reactor and to define dosing rates and cooling temperature to ensure process safety and product quality during production."

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Relevant Customer Publications

"DynoChem Applications in a Busy Pilot Plant", Pfizer (2013)

"Reaction Kinetics as a Tool to Underpin Control Strategies", GSK (2011)

"Thermal Scale-up – Vessel Characterization and Reaction Modelling with DynoChem", Roche (2011)

"Scaling Up and Plant-to-Plant Transfer of Safety Data for Exothermic Reaction", Merck (2011)

"A Data Driven Model Based Approach to Scale-up of Hydrogenation Reactions in the API Industry", Pfizer (2011)